SYN-AKE is an excellent anti-wrinkle active compound with a snake
venom-like mode of activity
SYN-AKE smoothes mimic wrinkles in a short period.
SYN-AKE age killing effect particularly effective against expression lines
SYN-AKE is an intensive anti-wrinkles care.
Efficacy Tests
In vitro tests:
The efficacy of the SYN-AKE tripeptide (at a concentration of 0.5mM) has been demonstrated in vitro by measuring the frequency of contraction of the innervated muscle cell as a function of the incubation time.
SYN-AKE peptide reduces muscle cell contraction and its action if reversible.
In vivi tests:
The measurement of the smoothing and anti-wrinkle effect of SYN-AKE (4%) was compared to a placebo. A cream was applied to the forehead twice daily during 28 days.
SYN-AKE - Age Killing Effect.
The smoothing effect (Ra) was measured on 80% of the volunteers and the anti-wrinkle effect (Rz, Rt) measured on 73% of the volunteers.
Results showed up to 52% of wrinkle size after 28 days application!
SYN-AKE is a new anti-wrinkle active compound based on a synthetic tripeptide that mimics the effect of waglerin 1, a peptide that is found in the venom of the Temple Viper, Tropidolaemus wagleri.
venom-like mode of activity
SYN-AKE smoothes mimic wrinkles in a short period.
SYN-AKE age killing effect particularly effective against expression lines
SYN-AKE is an intensive anti-wrinkles care.
Efficacy Tests
In vitro tests:
The efficacy of the SYN-AKE tripeptide (at a concentration of 0.5mM) has been demonstrated in vitro by measuring the frequency of contraction of the innervated muscle cell as a function of the incubation time.
SYN-AKE peptide reduces muscle cell contraction and its action if reversible.
In vivi tests:
The measurement of the smoothing and anti-wrinkle effect of SYN-AKE (4%) was compared to a placebo. A cream was applied to the forehead twice daily during 28 days.
SYN-AKE - Age Killing Effect.
The smoothing effect (Ra) was measured on 80% of the volunteers and the anti-wrinkle effect (Rz, Rt) measured on 73% of the volunteers.
Results showed up to 52% of wrinkle size after 28 days application!
SYN-AKE is a new anti-wrinkle active compound based on a synthetic tripeptide that mimics the effect of waglerin 1, a peptide that is found in the venom of the Temple Viper, Tropidolaemus wagleri.
Clinical Trial.
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